BrainEver platform is based on the translation of the work by Alain Prochiantz and colleagues on brain development and physiology. They demonstrated that homeoproteins, first identified as early developmental regulators, are also active throughout life, when they participate in the maintenance and protection of several neuronal populations. Homeoproteins control several neuronal functions, including epigenetic stability and metabolism.
The first project, BREN01, is Engrailed 1 for the treatment of Parkinson’s disease.
Homeoproteins are being explored to treat other neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), Huntington disease and some optic neuropathies.
RCS: 810 542 506 Paris – SIRET: 810 542 506 000 11
Registered capital: 38 500,00 €