Press Release

“BrainEver Receives FDA Orphan Drug Designation for BREN-02, (human recombinant Engrailed 1) for the
Treatment of Amyotrophic Lateral Sclerosis (ALS)”

 

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Publications

“The homeoprotein ENGRAILED-1 promotes motoneuron survival and sustains motor functions”

BioRxiv (2019)

Vargas Abonce S., Lebœuf M., Moya K.L., Prochiantz A.

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“Homeoprotein Neuroprotection of EmbryonicNeuronal Cells”

eNeuro (2019), 6(5)

Vargas Abonce S., Leboeuf M., Prochiantz A., and Moya K.L.

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“Engrailed-1 induces long-lasting behavior benefit in an experimental Parkinson primate model”

Mov Disord (2019), Jul;34(7):1082-1084

Thomasson N., Pioli E., Friedel C., Monseur A., Lavaur J.,  Moya K.L.,  Bezard E., Bousseau A., Prochiantz A.

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“Non-cell autonomous OTX2 transcription factor regulates anxiety-related behaviors in the mouse”

BioRxiv (2019)

Vincent C., Gilabert-Juan J., Alvarez-Fischer D., Di Nardo A.A., Krebs M.-O., Le Pen A., Prochiantz A.

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“OTX2 Signals from the Choroid Plexus to Regulate Adult Neurogenesis”

eNeuro (2019), 6(2)

Planques A., Oliveira Moreira V., Dubreuil C., Prochiantz A., and Di Nardo A.A.

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“Perineuronal nets in brain physiology and disease”

Seminars in Cell and Developmental Biology 89 (2019) 125–135

Testa D., Prochiantz A., Di Nardo A.A.

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“Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression”

The EMBO Journal (2018)

Blaudin de Thé FX., Rekaik H., Peze-Heidsieck E., Massiani-Beaudoin O., Joshi R.L., Fuchs J., Prochiantz A.

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“The Physiology of Homeoprotein Transduction”

Physiological Reviews (2018)

Di Nardo, A.A.,  Fuchs J., Joshi R.L., Moya K.L., Prochiantz A.

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“Non-cell Autonomous OTX2 Homeoprotein Regulates Visual Cortex Plasticity Through Gadd45b/g”

Cerebral Cortex (2018), 1–12

Apulei J., Kim N., Testa D., Ribot J., Morizet D., Bernard C., Jourdren L., Blugeon C., Di Nardo A.A., Prochiantz A.

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“Extracellular Pax6 Regulates Tangential Cajal–Retzius Cell Migration in the Developing Mouse Neocortex”

Cerebral Cortex (2018), 1–12

Kaddour H., Coppola E., Di Nardo A.A., Le Poupon C., Mailly P., Wizenmann A., Volovitch M., Prochiantz A., Pierani A.

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 “Homeoprotein signaling in the developing and adult nervous system”

Neuron (2015)

Prochiantz A., Di Nardo A.A.

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“Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress”

Cell Reports (2015)

Rekaik H., Blaudin de Thé FX., Fuchs J., Massiani-Beaudoin O., Prochiantz A., Joshi RL.

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Posters presented at the Movement Disorder Society International congress, Sept. 2019

“Increasing chances of detecting a neuroprotective signal in PhI /II PD clinical”

Palfi S.,  Bousseau A., Denot C., and Corvol JC.

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“A single nigral injection of human ENGRAILED-1 induces long lasting behavior benefit in an experimental primate PD model”

Prochiantz A., Pioli E., Friedel C., Moya K.L., Bezard E., and Bousseau A.

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